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have suggested that the intervention of rosuvastatin in mice with HFD resulted in a significant increase in the Lachnospiraceae and Erysipelotrichaceae families and a significant decrease in Proteobacteria phylum, Coriobacteriaceae, Akkermansiaceae family, and Akkermansia (115)

Arch Dermatol 1979;115:1116-7

PMID 40123442

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Oxidative stress triggered by AFB1 plays a crucial role in kidney damage and the antioxidant activity of Curcumin (CURC) could help in preventing such adverse effect

The underlying logic is straightforward: if each component supports a different aspect of fat metabolism, combining all three could provide synergistic metabolic support