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Macrophages are classified as either traditionally activated (M1-type) or alternatively activated (M2-type), which have opposing roles in inflammation (Kawanishi et al., 2010

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Furthermore, caspase signaling pathway would be activated to induce cell apoptosis and the development of kidney diseases (Sinha et al., 2013

[DOI] [PMC free article] [PubMed] [Google Scholar] 6.Townsend D.M., Tew K.D., Tapiero H