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GLP-1 medicines in arthritis and pulmonary inflammation A single dose of liraglutide administered before LPS exposure in mice was found to attenuate lung injury, reducing the expression of IL-6, IL-1, and TNF in the lungs

Semaglutide Semaglutide is a GLP-1 Agonist, FDA-approved for weight loss

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Sarah Armstrong, a member of the AAP guideline committee, stated in a 2023 AAP press briefing: "We do not have the evidence to support pharmacotherapy with GLP-1 agonists below age 12, and clinicians should not extrapolate from adolescent data to younger children without trial-level safety evidence." The Endocrine Society's pediatric obesity guideline similarly restricts pharmacotherapy recommendations to adolescents aged 12 and older when lifestyle interventions have been insufficient [7]

Host-microbe-drug-nutrient screen identifies bacterial effectors of metformin therapy