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5.2 Phase II: dose selection of semaglutide and SNAC Different combinations of semaglutide and SNAC doses were explored in phase I/II studies [59, 65]

It occurs more commonly with higher doses or when injecting on an empty stomach

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sequence modication 2.5 hours Beinaglutide PEGylation (Polyethylene glycol chain) 4 days Dulaglutide Fc fusion protein (Immunoglobulin) 4.7 days Fatty diacid side chain

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Due to its dual action, some studies suggest it might have a more favorable side effect profile