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In a randomised, double-blind, placebo-controlled trial, Lacto-Wolfberry (LWB) supplementation over three months in elderly individuals enhanced immune response to the influenza vaccine, demonstrating significantly higher post-vaccination serum influenza-specific IgG levels compared to placebo, without serious adverse effects [35]
The production of SCFA in the colon activates orphan G protein-coupled receptors which results in the production of peptide tyrosine tyrosine (PYY) and glucagon-like peptide 1 (GLP1) by enteroendocrine L cells (Tolhurst et al., 2012
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