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While western blot analyses or ELISAs can accurately determine the abundance of the LPL protein, this does not consider the presence or absence of activating (e.g., ApoC-II and ApoA-V), inhibiting (e.g., Angptl4, ApoC-I, and ApoC-III) factors, whether LPL has been unfolded, or is in an inactive state

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In the United States, most nutraceuticals are regulated as dietary supplements and food additives by the FDA