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3) is the maintenance of tissue homoeostasis at all the levels of CNS organisation, from molecular (ions, metabolites, and neurotransmitters, etc.), to network (regulation of synaptic connectivity), to organ (formation and maintenance of bloodbrain barrier and glymphatic clearance system) and systemic (chemosensing blood oxygen, Na + , CO 2 or glucose)

PMID 22479358

On a cellular level, things are happening