Some botanicals in the research literature have shown associations with GLP-1 pathway activity - but that's category-level, ingredient-level evidence, not a proven claim for this specific patch formulation
however, overall colon transit time was not significantly increased
Whether this should be regarded as specific metabolic treatment, targeting only the metabolic alterations of the syndrome, is debatable, since the improvement in metabolic conditions, e.g., insulin resistance, would tenably have a positive impact also in gonadal function in women with PCOS
BPC-157's cytoprotective effects are also linked to its interaction with the cellular cytoskeleton
Chhaya Makhija, MD, DipABLM Board-Certified Endocrinologist | Lifestyle Medicine Physician | Founder, Unified Endocrine & Diabetes Care Lafayette Fresno California Telemedicine (including Silicon Valley, Palo Alto, Menlo Park, San Francisco, Walnut Creek, Oakland, Sacramento) Watch or Listen to the Full Episode For a deeper dive into the science and real-world clinical nuance:
Ferraz M, Rho HS, Hemerich D, Henning HHW, van Tol HTA, Holker M, Besenfelder U, Mokry M, Vos P, Stout TAE, Le Gac S, Gadella BM (2018) An oviduct-on-a-chip provides an enhanced in vitro environment for zygote genome reprogramming