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it does not demonstrate that injecting synthetic MOTS-c into humans produces equivalent or superior metabolic benefits
Increased availability of cysteine alters redox status of cells 28,29 and enhances production of glutathione (GSH) 30,31 , which exerts redox effects and S-glutathiolation of proteins 32 , and production of hydrogen sulfide 30,31 , which increases minute ventilation (Ve) via actions in carotid bodies 33
Laboratory studies may show evidence of massive hepatic necrosis with elevated AST, ALT, bilirubin, and prolonged coagulation times (in particular, elevated prothrombin time)
Tests are chosen based on clinical suspicion and may include basic screens or in-depth hematology workups
Co-administration with prokinetic agents (e.g., domperidone) or antacids may alter absorption or worsen GI discomfort
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