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1 For those taking Wegovy HD, 89% achieved 5% or greater body weight loss versus 38% taking placebo (from a baseline body weight of 248 lb.)

It is known that the brains chemical messaging system involving neurotransmitters like norepinephrine, serotonin, and dopamine plays a significant role in regulating appetite

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While large clinical trials in type 1 diabetes showed that metformin had little effect on A1C and body weight, other research has shown that the same group does benefit from metformin, particularly for addressing insulin resistance

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