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Luteolins therapeutic potential is further constrained by fundamental biopharmaceutical limitations, including poor aqueous solubility, low membrane permeability, and extensive phase II metabolism, all of which restrict its oral bioavailability (Wang et al., 2024)

Lipo-GSH vs SAG: Performance & Technical Comparison Absorption Stability (Temperature & Acid/Alkali Resistance) Lipo-GSH Acid resistance: The phospholipid bilayer remains structurally intact in gastric acid (pH 1.53.5), effectively protecting encapsulated GSH from degradation

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