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Moreover, iron distribution in the brain is highly heterogeneous and region-specific

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This observation likely reflects that MIA-induced OA primarily targets cartilage, whereas changes of the subchondral bone occur secondarily and can be influenced by factors such as mechanical loading, individual variability, and baseline bone status 52

5.2 TCM compound Derived from Ye Tianshis Secret Formulas for Gynecological Syndromes, Wenshen Tiaojing Decoction was shown to significantly decrease oxidative stress markers and downregulate ferroptosis-related genes in a PCOS mouse model (104)

In our contemporary world, environmental toxins are ubiquitous