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These design elements increase the risk of bias for subjective clinical outcome assessments and may lead to the overestimation of treatment effects for both benefits and harms

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For LC-MS/MS a sample aliquot (transfer buffer) was diluted by half with acetonitrile and then, 10 L of this solution was injected into the analytical equipment made up a Liquid Chromatography system coupled to a triple quadrupole mass spectrometer Thermofisher TS Quantum Discovery or Waters Quattro Premier XE equipped with a electrospray ionization source

2019 ACCORD Study Group, Cushman WC, Evans GW, Byington RP, Goff DC Jr, Grimm RH Jr, et al

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