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Glucagon-like peptide-1 receptor agonists (GLP-1RAs) and sodiumglucose cotransporter-2 inhibitors (SGLT2is) both provide cardiovascular benefit, although their clinical profiles differ as SGLT2 inhibitors have shown greater reductions in HF hospitalization, whereas GLP-1 receptor agonists appear particularly effective in reducing atherosclerotic events such as stroke [5, 6]