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Plain sterile water is acceptable only for single-use experiments because there is no preservative for the multi-week draw window

To ease the analytical difficulties with limitations on sensitivity or specificity, previous applications often make use of cyanidation conversion of native B12 vitamers into CNCbl during sample preparation

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Keeping that distinction clear is the single most important framing point for a clinician encountering this compound

Curr Pharm Des 20:11211125 Shibuya M (2011) Vascular endothelial growth factor (VEGF) and its receptor (VEGFR) signaling in angiogenesis: a crucial target for anti- and pro-angiogenic therapies

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