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Vitamin B12 typically requires different timing

Alternative to surgery in some cases: For individuals hoping to avoid surgery (e.g., for tendon repair, ligament injury), the stack is sometimes promoted as a less invasive option, though this claim is based mostly on animal data and anecdotes

Important safety note : If folate deficiency is detected alongside B12 deficiency, B12 replacement must be started before folate to avoid worsening neurological symptoms

doi: 10.1210/jc.2006-2003

Your doctor may use injections if you have a severe B12 deficiency because you dont have enough of a protein called intrinsic factor

The authors recommend continued research into optimal treatment duration