You have to take it on an empty stomach when you first wake up
Zepbound has a list price of $1,086.37 for a 28-day supply without insurance
Box 1: Recent Trump Administration Obesity Drug Initiatives In November 2025, the Trump administration announced reaching a deal with Eli Lilly and Novo Nordisk to lower the cost of their GLP-1s for Medicare, Medicaid, and those purchasing the drugs directly from the manufacturers through a new TrumpRx website
If you remember the missed dose after Friday, skip the dosage and take the next one on Monday
Most are administered via pre-filled injection pens, though some are available in tablet form
Hims had the best reviews, he says, so he filled out an intake form on its site with info including his starting weight (around 350 pounds)