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While sauna use can promote detoxification, it also leads to significant fluid loss

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L-carnitine buffers excess acetyl-CoA inside the mitochondria by forming acetylcarnitine, which can reduce metabolic stress, support carbohydrate oxidation and improve efficiency during higher exercise intensities

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For example, the studies included in this meta-analysis involved varying the patient profiles, some of which included patients with more advanced metabolic disease conditions, potentially influencing the degree of weight reduction observed