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This cytoskeletal stabilization is thought to contribute to its observed effects on tendon and ligament healing in animal models, where organized collagen deposition and tissue strength are paramount

Women taking long-term medications such as metformin (for diabetes or polycystic ovary syndrome) or proton pump inhibitors (for acid reflux) may also have reduced B12 absorption

Asquith M, Elewaut D, Lin P, Rosenbaum JT (2014) The role of the gut and microbes in the pathogenesis of spondyloarthritis

Two notable adjuncts include: Platelet-Rich Plasma (PRP) PRP involves concentrating a patients own platelets and injecting them into the injured area