To Summarize Vitamin B12 injections side effects are incredibly rare, and when reactions occur, they are more likely due to additives rather than the B12 itself

Areas Without Adequate Human Evidence Cardiovascular safety Neurological and psychiatric effects Liver and kidney safety Effects on blood glucose in humans Effects on methylation pathways Genotoxicity Carcinogenicity Reproductive and developmental toxicity Use during pregnancy or breastfeeding Interactions with prescription medicines Interactions with supplements or research compounds Long-term exposure Product-Quality Risks Incorrect quinolinium compound Wrong substitution position Incorrect counterion Incorrect active-content calculation Residual starting materials Residual solvents Degradation products Heavy-metal or inorganic contamination Mismatched certificate of analysis Uncontrolled storage and transport Absence of published harm is not proof of safety A compound without routine regulated human exposure may generate very few formal safety reports simply because there is no organised pharmacovigilance system

An overview of Vitamin B12 Vitamin B12 (also called cobalamin) is a water-soluble vitamin
(PubMed) If AOD-9604 re-enters mainstream clinical availability through compliant channels, the most responsible use-case will likely be: carefully selected patients, realistic expectations, body composition focus, and as an adjunctnot a centerpiece
Those needing vitamin B12 supplements should consider vitamin B12 IV drips, which are designed to deliver optimal doses of vitamin B12 directly into the bloodstream, resulting in instant absorption and the fastest possible results
Drug Delivery Translational Research 9, 625630