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Furthermore, blockade of ET-1 receptors, mainly ETA, using antagonists such as atrasentan has demonstrated efficacy in reducing blood pressure and proteinuria, supporting the role of ET-1 in vascular and renal injury in CRHM syndrome (105)

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Compounded medications allow providers to adjust doses more precisely based on individual tolerance and response

It adds a second group: people who travel, live in warm climates, or manage multiple compounded medications, and it suggests raising those logistics with a provider in advance

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