It has been on the market since mid-2022 (Mounjaro) and 2023 (Zepbound), with millions of prescriptions filled
References 1 CornierMA
The treatment normalized serum corticosterone levels, enhanced central GABA and serotonin concentrations and reduced peripheral inflammation and gut microbiota profiling revealed a reduction in potentially pathogenic genera ( Acinetobacter, Enterococcus, Bacillus ) and increased abundance of beneficial taxa ( Muribaculum, Alistipes, Lactobacillus ), indicating the therapeutic potential of targeted psychobiotic intervention for stress-related disorders (Tyagi et al., 2025)
Brown SA, Kovatchev BP, Raghinaru D, et al
Key Takeaways from Marge Blanc: GLP is not a rigid process but one that adapts to the individual childs experiences and environment
S., Belaran, M., Rezaee, S., Naghesi, M., Mirzaei, H., & Tabrizian, K