does glp 1 cause irritability GLP-1 Medications: Everything You Need to Know Managing GI Discomfort on GLP-1s:

Activated POMC neurons process the precursor polypeptide POMC via the action of POMC by proprotein convertase subtilisin/kexin type 1 (PCSK1) to generate, among other peptides, -melanocyte-stimulating hormone (-MSH) [8]

Gen Comp Endocrinol (2018) 260:517

DM can impair immune function

Stay well-hydrated by drinking plenty of water, and avoid alcohol for at least 24 hours post-treatment, as alcohol can thin the blood and heighten the risk of bruising

Pretreatment (but not treatment) also reduced infarct size and partially restored complex II, IV and V activity and complex I, II, and III expression [78]

Consult a healthcare professional before using medication or starting any weight loss program