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Rl hexanoyl R2 is Tyr R3 lie n 5
[DOI] [PMC free article] [PubMed] [Google Scholar] Claes B
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Resnick N, Yahav H, Shay-Salit A, Shushy M, Schubert S, Zilberman LC, Wofovitz E (2003) Fluid shear stress and the vascular endothelium: for better and for worse
The reduced IGFBP affinity results in a dramatically extended half-life compared to native IGF-1, making IGF-1 LR3 valuable for laboratory research involving: Extended IGF-1 receptor activation studies Prolonged growth factor signaling pathway research IGFBP interaction and modulation studies Comparative studies with native IGF-1 For Canadian researchers studying growth factor pathways, IGF-1 LR3 provides a tool for understanding sustained receptor activation without the rapid clearance seen with native IGF-1
