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By contrast, the 70-year-old mother has osteopenia, a personal history of fracture, a maternal history of fracture, and FRAX scores that are high enough to warrant treatment

Interestingly, SFN has a unique ability in Nrf2 activation, which enhances the expression of heme oxygenase-1 (HO-1) and nicotinamide adenine dinucleotide phosphate quinone oxidoreductase 1 (NQO1) (59, 67), thereby protecting neurons from 6-hydroxydopamine (6-OHDA), methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) (68), amyloid (A) (69), and pro-inflammatory cytokines (70, 71)

GLP-1: Glucagon-like peptide

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In this state, the molecule has an extra electron available to donate to a free radical

Badran, M., Abuyassin, B., Golbidi, S., Ayas, N., & Laher, I