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Mitophagy stimulation as a novel strategy for the treatment of mitochondrial diseases

227231 These observations highlight the importance of vigilant monitoring and cautious dose adjustments to mitigate the risk of adverse reactions, ensuring the safe and effective utilization of these agents in the management of hyperuricemia and gout

163 At the lesion core therefore, all neural cells die by necrosis, which leads to a massive release of damage-associated molecular patterns (DAMPs), including release of glutamate and ATP, which propagate excitotoxicity

2, mitochondrial dynamics, including processes such as fission and fusion, are regulated by ROS such as hydrogen peroxide, which alters mitochondrial morphology and quantity in response to cellular energy demands and ROS levels (38)

Administration of fenugreek oil to these diabetic rats lead to a reduction in pancreatic -cell damage

10.1016/j.biochi.2018.04.022 74 ManfordA