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Drug Target 3 , 263271 (1995)

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Participants received tirzepatide 5 mg, 10 mg, or 15 mg once weekly or placebo for 72 weeks

Pyocyanin also initiates neutrophil extracellular trap (NET) formation (Rada et al., 2013) and aberrant NET release triggered by pyocyanin-mediated intracellular ROS production directly damages host tissues and has been linked to the severity of many diseases including CF (Rada et al., 2013)

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