People may also drink less fluid if they are eating less, which can make constipation worse
Research backs this up: when using GLP-1s to aid in weight loss, they were found to effectively reduce BMI, triglycerides, waist circumference, and total testosterone in people with PCOS, according to a 2024 meta-analysis in the Journal of Diabetes and its Complications
In this six-month prospective cohort study, 200 adults ages 18 to 65 with a BMI of 25 kg/m or higher (classified as overweight or obese) were enrolled and prescribed either the GLP-1 receptor agonist semaglutide or the dual GLP-1/GIP agonist tirzepatide
This triple-action approach creates a more comprehensive effect on metabolism compared to single or dual-receptor medications
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