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Mi Z, Graham SH
Mechanistically, this may relate to GHK-Cu's ability to upregulate matrix metalloproteinases (MMP-1, MMP-2), enzymes that can fragment collagen if their activity exceeds the body's ability to rebuild
10.1016/s0092-8674(00)81440-3 Cell 7 AnsarM.ParachaS
We have some more here: Human Fibroblast Conditioned Media - a growth factor cocktail used in some cosmetic products Insulin-like growth factor 1, aka sh-Oligopeptide -2 - a pal of EGF composed of 70 amino acids Vascular Endothelial Growth Factor, aka Sh-Polypeptide-9 - part of a GF cocktail trade named BIO-Placenta Sh-Oligopeptide-2 is also called Insulin-like growth factor 1 and it belongs to the same group of ingredients (Growth Factors) as its better-known sister, Epidermal Growth Factor or Sh-Oligopeptide-1
Science 284 , 455461 (1999)
van Loevezijn, A
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