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1 50% sustained eGFR decline occurred in 165 patients (9.3%) on Ozempic and 213 patients (12.1%) on placebo

Conversely, a few studies reported high levels of vitamin B12 in the blood of patients with a worse COVID-19 outcome 48,49 potentially due to cytolysis leading to the release of intracellular B12 into the plasma and disrupted B12 clearance by the liver, which is often affected in these patients 50

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Both Semaglutide and Tirzepatide offer powerful tools for managing weight, with each medication bringing unique benefits to the table