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In overweight cats, L-carnitine has been studied for supporting fat metabolism and body condition

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Keeping your muscle strong helps protect your metabolism, burn calories more efficiently, and makes it easier to lose weight and keep it off long-term

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doi: 10.1016/j.bpj.2009.06.021 153 SardeliAVTomeleriCMCyrinoESFernhallBCavaglieriCBChacon-MikahilMPTet al

Additionally, the promoter of peroxisome proliferator-activated receptor gamma, coactivator 1 alpha (PGC-1/PPARG) has two AREs, although they have not been validated as functional, and has been reported to be both up- and downregulated by NRF2 activation depending on the context (OBrien et al., 2015)