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Weight loss treatment is contraindicated in pregnancy and fetal safety hasn't been established

And in the randomized trials of these GLP-1 medications, about 14% to 38% of participants didn't achieve at least 5% weight loss

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Emerging 2025 research suggests semaglutide (the drug in Ozempic and Wegovy) is associated with lower RA disease activity, less pain, and improved joint outcomes especially in patients who also carry excess weight

These hypothetical examples show how eligibility, documentation, and plan design can lead to different decisions