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Low to moderate levels of ROS contribute to sustaining cellular proliferation and can be a trigger for the activation of the stress-responsive survival pathway, including the glucose transporter 3,4

68 Mooradian AD, Wong NC, Shah GN

These factors increase your body's need for antioxidants

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Although the above experimental and clinical studies have demonstrated the feasibility of metformin in treating gliomas, including suppressing cell proliferation and extending survival, these findings provide new strategies and directions for metformins application in glioma treatment

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