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Despite their popularity, GLP-1 receptor agonist use to date has been limited to patients willing and able to administer the medication by SC injection

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Concomitant medications in cases of GLP-1 RA-related NAEs mirrored patterns observed in all NAE cases, with frequent co-administration of oral antidiabetics and insulin (Fig

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Important issues to review include nausea, vomiting, constipation, diarrhea, reflux, hydration status, protein intake, muscle preservation, diabetes medications, gallbladder symptoms, kidney function, history of pancreatitis, thyroid and family history considerations, and long-term maintenance strategy

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