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However, in guidelines published in 2012, the British Columbia Medical Association (Canadian Ministry of Health) recommended a dose of 1000 g/day for pernicious anemia or food-bound cobalamin malabsorption [34]

Because these mechanisms reinforce one another, the overall metabolic effect can appear robust even if any single component varies, which is another reason a clean, isolated read on the gastric-emptying contribution is so hard to obtain from combination-drug outcome data

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