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Immunofluorescence imaging revealed that FITC-labeled exendin 939 was bound to TRPV1 on the cell surface in CHO K1 cells expressing human TRPV1 but not in nave CHO K1 cells (Fig

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[7] [17] Gastrointestinal side effects including nausea, vomiting, diarrhea, constipation, and abdominal discomfort affect 2050% of patients, particularly during dose escalation periods

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However, this is often only if the appropriate medication is not available