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Participants were asked to respond as quickly and accurately as possible by pressing a keyboard button to visual stimuli appearing in a random frequency (210 s presentation interval)

Nitrous oxide, a commonly used anesthetic, oxidizes and inactivates vitamin B 12 , thus inhibiting both of the vitamin B 12 -dependent enzymes, and can produce many of the clinical features of vitamin B 12 deficiency, such as megaloblastic anemia and neuropathy

Follow standard lyophilized peptide handling protocols