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Immunology (2016) 149(2):14656

Coffee and its effects on the immune system

Blood Cells Mol Dis 2003

Some prefer the once-weekly simplicity

The results showed that M1 macrophages and CD8+ T cells were significantly increased in RA tissues compared to normal tissues, while M2 macrophages, resting mast cells, and dendritic cells were decreased, indicating substantial alterations in the RA immune microenvironment characterized by increased pro-inflammatory and decreased anti-inflammatory cells, potentially contributing to persistent inflammation

Further, increased mitochondrial oxygen and decreased ROS in the liver were also observed