By maintaining a microdose, patients may be able to achieve the desired effects of the drug while avoiding the dose threshold that triggers severe GI effects, resulting in a better overall experience and adherence to the treatment
References For Further Reading (1) K Raun, B S Hansen, N L Johansen, et al (1998) Ipamorelin, the first selective growth hormone secretagogue European Journal of Endocrinology, 1998 Nov, Volume 139 (Issue 5), Pages 552-61
These common reactions can feel worse when the dose increases
This review summarises the literature on this topic, including a meta-analysis of published studies on GLP-1 secretion in individuals with and without diabetes after oral glucose and mixed meals
dose-for-dose equivalence is not 1:1 Dosing frequency is typically once or twice daily Storage requirements depend on the formulation and should be confirmed with the compounding partner Because dose is formulation-specific and compounding preparations vary, physicians should work with their compounding partner to confirm the specific dose and protocol appropriate to the formulation they prescribe
& Tsao, T
