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Mitochondrial dysfunction induces muscle atrophy during prolonged inactivity: a review of the causes and effects

Balancing good bowel movements and inducing diarrhea using laxatives in PD patients requires a delicate approach by the management team, including a nephrologist, PD nurses, and dieticians

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On the EPIC Study website, it specifically states: "Currently there is no treatment licensed to delay the onset of CHF [congestive heart failure]." Elsewhere on the EPIC Study website it states: "There is currently no treatment licensed for the management of preclinical, myxomatous mitral valve disease (MMVD)." And still on another page of the EPIC Study website it states: "Treatment of CHF due to MMVD begins when the dog shows clear clinical signs of heart failure, and is tailored for the individual dog." As you see, pimobendan's own manufacturer repeatedly warns against giving the drug to dogs before they are in heart failure