In it, the mutation appears in the 188 amino acid, with substitution of phenylalanine (Phe) by serine (Ser) 37
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Weakness and numbness in the hands and feet: Vitamin B12 deficiency can cause nerve damage, which can result in numbness or tingling in the hands and feet, as well as muscle weakness
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Kidney Disease: Improving Global Outcomes Work Group (KDIGO) 2022 clinical practice guideline for diabetes management in chronic kidney disease
Accessed via Physiology, Obesity Neurohormonal Appetite And Satiety Control
