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Available as: Last cited 6 Sept 2023 Purnell JQ (2000) Definitions, Classification, and Epidemiology of Obesity

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Based on published trial data to date, serious side effects were relatively uncommon in controlled clinical trial settings

4d, e), in agreement with recent reports which also indicate SPHKAP localisation and PKA-RI targeting to the ER 32,33

In response to these and other data, including a meta-analysis of 42 trials suggesting that rosiglitazone was associated with increased risk of MI (34), the FDA briefly issued a black box warning for cardiovascular risk with rosiglitazone in 2007