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It works externally on fat deposits and fat deposits alone

The clinical relevance in humans is still unclear, but the current guidance is that retatrutide should not be used in people with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2

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The newer, longer-acting versions like Ozempic and Wegovy were approved more recently (Ozempic in 2017, Wegovy in 2021), but theyve been studied in large clinical trials involving thousands of patients over several years

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