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Clinical studies on GLP-1 receptor agonists show that patients may experience significant weight reduction over time, especially when treatment is combined with healthy nutrition and regular physical activity

GLP-1 is able to stimulate cAMP formation in RIN 1046-38 cells, which in turn causes an increase in insulin mRNA levels and insulin release, and insulin accumulation in the culture fluid was observed by adding GLP-1 (7-37) to RIN 1046-38 cells for 1 h incubation (Drucker et al., 1987)

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Available from: Hanna Huber 1, Alina Schieren 2, Jens Juul Holst 3, Marie-Christine Simon 4 Dietary impact on fasting and stimulated GLP-1 secretion in different metabolic conditions a narrative review

Endocr Rev 2018;39:71938 72

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