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Tirzepatide, a dual GIP and GLP-1 receptor agonist approved for type 2 diabetes and chronic weight management, commonly causes gastrointestinal effects including nausea, diarrhea, and constipation

A larger share, 60% , cover GLP-1s for diabetes only, and 45% cover them for other FDA-approved conditions such as sleep apnea and cardiovascular disease

Scientific interest has focused on how combined receptor activity may affect appetite signaling, energy balance, glucose regulation, insulin-related pathways, and lipid metabolism

This article is for educational purposes only and does not constitute medical advice

Beyond glycemic control, these medications initially slow gastric emptying, though this effect may diminish over time with long-acting formulations

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