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As they die, patients gradually lose muscle control and eventually develop life-threatening respiratory failure

& Shakibaei, M

Follow up treatment of NSD2 HiBit cells with UNC10415667 in a dose response fashion revealed a DC 50 value (concentration at which 50% of NSD2 is degraded) of 460 nM, which is about 2-fold more potent than UNC8732 and UNC10088 in the same assay (Fig