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CCl4-treated animals showed an altered lobule structure through paraplastic connective tissue, and mild to serious fibrosis was detected (Figure 7C,E) compared to the sham group (Figure 7B,E)

10.1038/cdd.2009.107 Cell Death Differ

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In addition, ONO-3411 showed some degree of benefit in animal models of cardiovascular and cerebral ischemia/reperfusion (Halliwell and Gutteridge, 2015)

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