Patients with kidney disease, cardiovascular problems, history of peptic ulcers, or those taking anticoagulants should consult their GP before combining these medications
Body weight plays a role in this variation, though it is not the only factor
Patients with certain genetic profiles may need higher starting doses, dual-compound therapy, or alternative peptide pathways to achieve weight loss
Valproate-induced hyperammonemic encephalopathy and normal liver functions: possible synergism with topiramate
Researchers are also exploring their potential benefits for things like smoking cessation, substance use disorders, and even polycystic ovary syndrome (PCOS), widening their impact far beyond diabetes and obesity
Juergens H, Daw NC, Geoerger B, Ferrari S, Villarroel M, Aerts I, et al