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Owing to the overproduced H 2 O 2 and GSH in tumor cells, TeNW can selectively eliminate cancer cells while normal cells survive (Figure 1J)

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The apoE / mice fed with dietary TMAO for 8 weeks were found to have increased atheromatous plaques in the aorta and elevated serum lipids compared to the control group, which was demonstrated to be due to the inhibition of hepatic bile acid synthesis in mice possibly by downregulating Cyp7a1 (i.e., cholesterol 7-hydroxylase, the key regulatory enzyme of hepatic bile acid biosynthesis) (Ding et al., 2018)

EBITDA margin guidance of 30-32% going forward is conservative relative to the 33.6% delivered in FY26 management is building in a buffer for geopolitical uncertainty and the loss of PLI benefits