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Moreover, knockdown of ATG5 inhibits TMAO-induced autophagy and cardiac hypertrophy, indicating that TMAO modulates cardiac hypertrophy through targeting the pathway mediated by ATG5-dependent autophagy

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These findings are supported by a prospective study on VLCKD intervention [135] showing an average weight loss of approximately 20 kg over 4 months, primarily due to reductions in total and visceral FM (~ 85% of total loss), while LMB and muscle strength were preserved

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ALC is a type of carnitine produced naturally in the brain

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Another study has shown that the HCV core antigen quantification could be an alternative to the HCV RNA quantification for on-treatment antiviral response monitoring[274]

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Disorders such as bacterial cystitis, urinary calculi, vaginitis, and less common problems like carcinoma in situ of the bladder and chronic bacterial prostatitis have significant symptom overlap and must be systematically excluded or identified and treated appropriately

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It might not work for severe injuries

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